Cancer Guidelines Database

Access quality cancer guidelines from a single Canadian source

We've listed 22 guidelines under your selection of "Location". The most recent guidelines are first.

Indications for Use of Breast Magnetic Resonance Imaging (MRI)

Year: 2017
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for the appropriate use of breast magnetic resonance imaging (MRI). The guideline examines indications for breast MRI use, such as for the screening of high risk individuals, for problem solving when mammographic, sonographic or clinical findings are suspicious but inconclusive, for the assessment of positive margins following breast cancer surgery or neoadjuvant chemotherapy, and for the assessment of breast implant integrity.

Guideline: Influenza Vaccine for Ambulatory Oncology Patients

Year: 2017
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for adult patients with solid tumour malignancies. The guideline provides recommendations for administering influenza vaccines to these patients. The timing of vaccination, and for whom vaccination is appropriate, are both discussed.

Molecular Biomarker Discordance between Primary and Recurrent/Metastatic Breast Cancer

Year: 2016
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for patients with a history of breast cancer. The guideline examine the use of biopsies and retesting of estrogen receptor (ER), progesterone receptor (PR) and HER2-neu receptor (HER2) to determine recurrence or metastases. Outcomes of interest include progression-free and overall survival.

Guideline for the Ordering, Preparation and Administration of Chemotherapy

Year: 2015
AGREE II score: Unavailable
Developer organization: Eastern Health
An organizational guideline for the processing and administration of chemotherapy to cancer patients. This guideline is an update to the 2013 guideline of the same title. The guideline examines the different stages and stakeholders in the chemotherapy treatment process, and the roles and responsibilities therein. Important aspects include accountability checks and staff safety procedures.

Guidelines for the Management of Febrile Neutropenia in Children

Year: 2015
AGREE II score: Unavailable
Developer organization: Atlantic Provinces Pediatric Hematology Oncology Network
This is a guideline for management of fever and neutropenia in children with cancer and/or undergoing hematopoietic stem cell transplantation. The guideline reviews patient evaluation and provides recommendations on initial management, with considerations made to patient condition and whether or not they are already receiving empiric antibiotics. Recommendations are also provided for continued management of inpatients, management based on culture results, and management of fever in hematology/oncology patients who have completed therapy or are on therapy but are not neutropenic.

Guidelines for the Management of Febrile Neutropenia

Year: 2014
AGREE II score: Unavailable
Developer organization: Atlantic Provinces Pediatric Hematology Oncology Network
This clinical practice guideline is for children with cancer and/or undergoing hematopoietic stem cell transplantation. The guideline reviews evaluation and management of fever and neutropenia, including initial empiric antibiotic selection, continued management of inpatients, and management based on culture results. Management of fever in hematology/oncology patients who have completed therapy and/or are on therapy but are not neutropenic is also discussed.

Neoadjuvant Treatment of Primary Breast Cancer

Year: 2014
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients with a pathological confirmed diagnosis of breast cancer. The guideline reviews diagnostic assessment, staging, and neoadjuvant treatment regimes depending on whether breast cancer is operable or inoperable. The guideline also discusses challenges involved with neoadjuvant therapy.

Treatment of Borderline Resectable and Locally Advanced Pancreatic Cancer

Year: 2014
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients diagnosed with borderline resectable or locally advanced pancreatic cancer. The guideline reviews pre-treatment staging, therapeutic options including biliary decompression and neoadjuvant therapy, chemotherapy with and without gemcitabine, chemoradiation therapy (CRT), induction chemotherapy and CRT, and radiological re-evaluation. Outcomes of interest include survival (median, overall, progression-free), treatment toxicity, adverse events, and surgical resectability rates.

Neo-adjuvant Treatment of Stage II and Stage III Rectal Cancer

Year: 2014
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients with a pathological confirmed diagnosis of locally advanced rectal cancer following appropriate radiological staging investigations. The guideline reviews treatment options including chemoradiation regimes and timing (adjuvant vs neo-adjuvant). Treatment related toxicities are also discussed. Outcomes of interest include overall survival, local recurrence, tumour response, and toxicity (acute and chronic).

Therapeutic Use of Myeloid Growth Factors for Chemotherapy-Induced Neutropenia in High Risk and Intermediate Risk Patients

Year: 2013
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients who are receiving systemic therapy for solid tumors, lymphoma and non-myeloid malignancies, and that are deemed at increased risk for developing febrile neutropenia as a result of myelosuppression. The guideline reviews the therapeutic use of myeloid growth factors (granulocyte-colony stimulating factors (G-CSFs), filgrastim and pegfilgrastim) in the prevention of chemotherapy induced neutropenia (CIN) according to patient risk for developing CIN.

Sentinel Node Biopsy in Breast Cancer

Year: 2013
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a guideline for patients who have been diagnosed with cancer of the breast and meet the selection criteria for sentinel lymph node biopsy (SLNB). The guideline reviews SLNB versus axillary lymph node dissection (ALND) and provides recommendations on patient selection, optimal technique for the use of SLNB, and surgical training. Recommendations are provided for managing challenging situations including ALND when SN is positive, intraoperative assessment of SN(s), ductal carcinoma in situ (DCIS), and multiple sentinel nodes.

Pre-operative Staging of Primary Rectal Cancer

Year: 2013
AGREE II score: Unavailable
Developer organization: Eastern Health
This clinical practice guideline provides recommendations on optimal staging investigations for patients with newly diagnosed primary cancer of the rectum. Diagnostic procedures are reviewed including digital rectal examination (DRE), rigid proctoscopy, total colonoscopy, Intraluminal Endoscopic Ultrasound (EUS), Magnetic Resonance Imaging (MRI), Computed Tomography (CT) , and Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)/CT Scanning. Outcomes of interest include test sensitivity and specificity.

Hormonal Treatment of In-Situ Breast Carcinoma

Year: 2012
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for the hormonal treatment of ductal carcinoma in situ. The guideline examines the use of tamoxifen for patients with ductal carcinoma in situ or lobular carcinoma in situ, and provides a recommended treatment plan.

Guideline for the Ordering, Preparation and Administration of Chemotherapy

Year: 2012
AGREE II score: Unavailable
Developer organization: Eastern Health
An organizational guideline for the processing and administration of chemotherapy to cancer patients. The guideline examines the different stages and stakeholders in the chemotherapy treatment process, and the roles and responsibilities therein. Important aspects include accountability checks and staff safety procedures.

Indications for Use of Breast Magnetic Resonance Imaging (MRI)

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for the use of MRI in breast cancer screening for patients who have hereditary risk, or have had previous radiation. The guideline examines indications and contraindications for breast MRI in screening, assessment, evaluation of treatment, and follow up. Outcomes of interest include MRI sensitivity and specificity.

Breast Magnetic Resonance Imaging (MRI) and High Risk Hereditary Breast Cancer

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for women at high risk for hereditary breast cancer. The guideline examines the efficacy of breast magnetic resonance imaging and recommends screening intervals. Outcomes of interest include improved hereditary screening, reduced mortality through early screening, and reduced false positives.

Recommendations for Use of Immediate Breast Reconstruction in Early-Stage Breast Cancer

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for immediate breast reconstruction in women with early stage breast cancer. The guideline examines the oncological safety of immediate reconstruction based on recurrence, risk of delay in adjuvant chemotherapy, and complication rates. The disadvantages of reconstruction before radiation therapy are also discussed.

The Management of Cancer Pain in Adults

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline on the management of pain in cancer patients. The guideline reviews pathophysiology, assessment, and treatment of cancer related pain. Pharmacological treatment options are reviewed in detail, including drug options and corresponding administration, dosage and schedule. Opioid tolerance, independence, and addiction are also discussed, as is the recommended treatment of opioid related side effects.

The Risk Reduction and Management of Secondary Lymphedema

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients who are at risk for or whom have been diagnosed with secondary lymphedema. The guideline reviews staging and provides recommendations on management and risk reduction strategies for secondary lymphedema. Treatment of secondary infections is also reviewed.

Chemoprevention of Breast Cancer in High Risk Patients

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for managing patients at high risk for breast cancer. The guideline examines potential chemopreventative treatments, specifically hormonal treatments, for all premenopausal patients ≥ 35 years of age and postmenopausal patients who are deemed high risk for possible breast cancer. Outcomes of interest include risk of recurrence and treatment side effects.

Staging of Primary Breast Cancer

Year: 2011
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for asymptomatic patients with recently diagnosed primary breast cancer who have already undergone surgical resection. Recommendations are provided for staging investigations, and procedures including bilateral mammography, biopsy, ultrasound, and MRI are discussed.