Cancer Guidelines Database

Access quality cancer guidelines from a single Canadian source

We've listed guidelines under your selection of "Location". The most recent guidelines are first.

Indications for Use of Breast Magnetic Resonance Imaging (MRI)

Year: 2017
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for the appropriate use of breast magnetic resonance imaging (MRI). The guideline examines indications for breast MRI use, such as for the screening of high risk individuals, for problem solving when mammographic, sonographic or clinical findings are suspicious but inconclusive, for the assessment of positive margins following breast cancer surgery or neoadjuvant chemotherapy, and for the assessment of breast implant integrity.

Guideline: Influenza Vaccine for Ambulatory Oncology Patients

Year: 2017
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for adult patients with solid tumour malignancies. The guideline provides recommendations for administering influenza vaccines to these patients. The timing of vaccination, and for whom vaccination is appropriate, are both discussed.

Molecular Biomarker Discordance between Primary and Recurrent/Metastatic Breast Cancer

Year: 2016
AGREE II score: Unavailable
Developer organization: Eastern Health
A clinical practice guideline for patients with a history of breast cancer. The guideline examine the use of biopsies and retesting of estrogen receptor (ER), progesterone receptor (PR) and HER2-neu receptor (HER2) to determine recurrence or metastases. Outcomes of interest include progression-free and overall survival.

Guideline for the Ordering, Preparation and Administration of Chemotherapy

Year: 2015
AGREE II score: Unavailable
Developer organization: Eastern Health
An organizational guideline for the processing and administration of chemotherapy to cancer patients. This guideline is an update to the 2013 guideline of the same title. The guideline examines the different stages and stakeholders in the chemotherapy treatment process, and the roles and responsibilities therein. Important aspects include accountability checks and staff safety procedures.

Guidelines for the Management of Febrile Neutropenia in Children

Year: 2015
AGREE II score: Unavailable
Developer organization: Atlantic Provinces Pediatric Hematology Oncology Network
This is a guideline for management of fever and neutropenia in children with cancer and/or undergoing hematopoietic stem cell transplantation. The guideline reviews patient evaluation and provides recommendations on initial management, with considerations made to patient condition and whether or not they are already receiving empiric antibiotics. Recommendations are also provided for continued management of inpatients, management based on culture results, and management of fever in hematology/oncology patients who have completed therapy or are on therapy but are not neutropenic.

Pre-operative Staging of Primary Rectal Cancer

Year: 2013
AGREE II score: Unavailable
Developer organization: Eastern Health
This clinical practice guideline provides recommendations on optimal staging investigations for patients with newly diagnosed primary cancer of the rectum. Diagnostic procedures are reviewed including digital rectal examination (DRE), rigid proctoscopy, total colonoscopy, Intraluminal Endoscopic Ultrasound (EUS), Magnetic Resonance Imaging (MRI), Computed Tomography (CT) , and Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)/CT Scanning. Outcomes of interest include test sensitivity and specificity.

Neo-adjuvant Treatment of Stage II and Stage III Rectal Cancer

Year: 2014
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients with a pathological confirmed diagnosis of locally advanced rectal cancer following appropriate radiological staging investigations. The guideline reviews treatment options including chemoradiation regimes and timing (adjuvant vs neo-adjuvant). Treatment related toxicities are also discussed. Outcomes of interest include overall survival, local recurrence, tumour response, and toxicity (acute and chronic).

Treatment of Borderline Resectable and Locally Advanced Pancreatic Cancer

Year: 2014
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a clinical practice guideline for patients diagnosed with borderline resectable or locally advanced pancreatic cancer. The guideline reviews pre-treatment staging, therapeutic options including biliary decompression and neoadjuvant therapy, chemotherapy with and without gemcitabine, chemoradiation therapy (CRT), induction chemotherapy and CRT, and radiological re-evaluation. Outcomes of interest include survival (median, overall, progression-free), treatment toxicity, adverse events, and surgical resectability rates.

Sentinel Node Biopsy in Breast Cancer

Year: 2013
AGREE II score: Unavailable
Developer organization: Eastern Health
This is a guideline for patients who have been diagnosed with cancer of the breast and meet the selection criteria for sentinel lymph node biopsy (SLNB). The guideline reviews SLNB versus axillary lymph node dissection (ALND) and provides recommendations on patient selection, optimal technique for the use of SLNB, and surgical training. Recommendations are provided for managing challenging situations including ALND when SN is positive, intraoperative assessment of SN(s), ductal carcinoma in situ (DCIS), and multiple sentinel nodes.