Sentinel Lymph Node Biopsy and Axillary Node Dissection in Early Stage Breast Cancer

A clinical practice and professional guideline that seeks to establish a standard of care in Alberta for the management of axillary nodes in patients with newly diagnosed, early-stage breast cancer. The guideline compares sentinel lymph node biopsy (SLNB) with axillary lymph node dissection (ALND) for axillary staging, and provides recommendations for management of positive biopsy results. Technical and operational considerations are also discussed. Outcomes of interest include false-negative rates and survival.