Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Ocology Clinical Practice Guidelines

This is a clinical practice guideline for adults treated for malignancy who are at risk of developing fever and neutropenia. The guideline discusses the prevention of infection in patients at risk for febrile neutropenia (FN) including risk assessment and use of antimicrobial prophylaxis, as well as the management of outpatients with FN including patient selection and empiric therapy. Outcomes of interest include risk of febrile episodes and infections, incidence of FN, overall mortality, infection-related mortality, and adverse effects of antimicrobials.