Surrogate Markers Predicting Overall Survival for Lung Cancer: ELCWP Recommendations

This clinical practice guideline examines the use of early intermediate criteria (surrogate markers) to predict treatment efficacy in patients with lung cancer including SCLC, NSCLC, and other histological types of pulmonary malignancies. The guideline examines the validity of several intermediate markers as surrogate end-points in lung cancer including time to progression, objective morphological response to chemotherapy, quality of life, downstaging after induction chemotherapy, and metabolic response.