Special Treatment Issues in Non-small Cell Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

This is a clinical practice guideline for patients with unique forms of NSCLC that require special consideration, including patients with Pancoast tumors, T4 N0,1 M0 central tumours, chest wall involvement, additional pulmonary tumour nodules, synchronous and metachronous second primary lung cancers (SPLCs), multifocal lung cancer (MFLC), and solitary metastases. Diagnostic and staging procedures are reviewed and recommendations are made for treatment options including surgical resection, chemotherapy, and radiotherapy. Outcomes of interest include 5-year survival, mortality, accuracy of treatment procedures, complications, mortality, and cost-effectiveness.