Optimal Excision Margins for Primary Cutaneous Melanoma

This is a clinical practice guideline for adult patients with malignant melanoma. The guideline discusses minimal optimal excision margins for melanoma, in general, with special consideration to melanomas of the face and distal extremities. Interventions considered include excisional biopsy, radiotherapy, topical imiquimod, Mohs micrographic surgery, sentinel node biopsy (SNB) and wide local excision. Outcomes of interest include survival, recurrence rate, and rate of local control.