Preoperative or Postoperative Therapy for Resectable Esophageal Cancer

This is a clinical practice guideline for adult patients with resectable, operable, and potentially curable thoracic (lower two thirds of esophagus) esophageal cancer for whom surgery is considered appropriate. The guideline compares treatment regimes including pre- and postoperative chemotherapy and/or radiotherapy versus surgery alone. Outcomes of interest include treatment related mortality, local control, survival benefits, and adverse effects.