Initial Staging of Squamous Cell Carcinoma of the Oral Cavity, Larynx and Pharynx (Excluding Nasopharynx) Part I: Locoregional Extension Assessment

This clinical practice guideline is part 1 of a 3 part series on the initial staging of squamous cell carcinoma of the oral cavity, larynx and pharynx (excluding nasopharynx). This guideline discusses locoregional extension assessment and provides recommendations on clinical and endoscopic examination, imaging assessment, and time to treatment. Outcomes of interest include effectiveness of diagnostic aids in early detection, sensitivity and specificity of imaging techniques, and impact of interval to initiation of radiation therapy on results.