The Role of Imaging in the Management of Adults with Diffuse Low Grade Glioma: A Systematic Review and Evidence-Based Clinical Practice Guideline

This is a clinical practice guideline for adults with a newly diagnosed lesion with a suspected or histopathologically proven low grade glioma (LGG). The objectives of the guideline are to provide recommendations on the role of imaging for management of LGG including optimal imaging techniques for both diagnsosis and follow-up, as well as imaging sequence and parameters. Techniques discussed include anatomic MR imaging, perfusion weighted MR imaging, diffusion weighted MR imaging, MR spectroscopy, PET and SPECT imaging. Primary outcome of interest is diagnostic specificity, as well as sensitivity and predicitve data.