Guideline for the Management of Clostridium Difficile Infection In Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients

This is a clinical practice guideline for the prevention and treatment of clostridium difficile infection (CDI) in children and adolescents with cancer as well as in pediatric hematopoietic stem-cell transplantation (HSCT) patients. The guideline provides initial treatment recommendations for non-severe, severe and recurrent CDI. The efficacy and appropriateness of probiotics, monoclonal antibodies and fecal microbiota transplantation are also considered.