Diagnosis, Prevention, and Management of Bleeding Episodes in Philadelphia-Negative Myeloproliferative Neoplasms: Recommendations by the Hemostasis Working Party of the German Society Of Hematology And Medical Oncology (DGHO) and the Society of Thrombosis and Hemostasis Research (GTH)

This is a clinical practice guideline for patients with myeloproliferative neoplasms (MPN). The guideline examines the diagnosis, management, and prevention of severe bleeding complications in patients diagnosed with classic Philadelphia chromosome negative (Ph-negative) MPN. Bleeding due to alterations of primary hemostasis, secondary hemostasis, and vascular alterations are discussed. Management of elective surgery in MPN patients is also examined.