Diagnosis and Empirical Treatment of Fever of Unknown Origin (FUO) in Adult Neutropenic Patients: Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society Of Hematology and Medical Oncology (DGHO)

This is a clinical practice guideline for fever of unknown origin (FUO) in adult neutropenic patients. The guideline updates recommendations for diagnosis and empirical therapy of these patients in light of the challenges of antimicrobial stewardship. Specific recommendations are provided for taking down patient history and performing a physical examination, ordering chest radiograph, and taking nasal/pharyngeal (MRSA) or rectal (VRE) swabs.