Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Chemotherapy in the Management of Adults With Newly Diagnosed Metastatic Brain Tumors

This clinical practice guideline is part of a series of guidelines for the management of adult patients with newly diagnosed metastatic brain tumours, excluding radiosensitive tumour histologies. The guideline discusses the use of chemotherapy for the treatment of these patients, and examines the use of chemotherapy alone, chemotherapy in addition to whole brain radiation therapy (WBRT), and chemotherapy in addition to stereotactic radiosurgery (SRS). The sequence of treatments and number of chemotherapeutic regimens are also considered.