Management of Cancer-Associated Anemia With Erythropoiesis-Stimulating Agents: ASCO/ASH Clinical Practice Guideline Update

This is a clinical practice guideline on the use of erythropoiesis-stimulating agents (ESAs) and biosimilars for the management of cancer-associated anemia in adult patients. Outcomes of interest include mortality, frequency of RBC transfusion, thromboembolic risk, quality of life, fatigue, progression-free survival and overall survival. In the case of biosimilars, hemoglobin (HgB) response and immunogenicity were additional outcomes of interest. Patient counselling and talking tips are also included to help clinicians implement the guideline’s recommendations.